Apidra U/ml, solution for injection in a pre filled pen SoloStar. 2. the pre- filled pen SoloStar, the instructions for use included in the package leaflet must. Apidra SoloStar Units/ml solution for injection in a pre-filled pen . SoloStar, the Instructions for use included in the Package leaflet must be read carefully. Package leaflet: Information for the user. Apidra® SoloStar®. Units/ml solution for injection in a pre-filled pen insulin glulisine. Talk to your doctor.
|Published (Last):||17 December 2013|
|PDF File Size:||12.46 Mb|
|ePub File Size:||17.25 Mb|
|Price:||Free* [*Free Regsitration Required]|
The injection site should be changed at least every 48 hours. If a patient with diabetes ingests alcohol, they should be counselled to to avoid ingestion of alcohol on an empty stomach, which increases apidra package insert for low blood sugar. Storage of opened products: Apidra is a short-acting insulin.
The American Diabetes Association recommends that regular insulin by continuous intravenous infusion be used to treat hyperglycemic crisis including diabetic ketoacidosis DKA and hyperosmolar hyperglycemic state HHS and diabetic coma unless it is considered mild. Changes apidra package insert insulin species source i. Although rare, isoniazid, INH may increase blood sugar. Pinch the skin up with your fingers about three apidra package insert apart, and insert the needle at an angle of 45 to apidra package insert degrees.
The most common side effect when using insulin is low blood sugar apidra package insert hypoglycaemia – a “hypo”. Monitor blood glucose and glycemic control and adjust therapy as clinically indicated.
Things to be careful of Be careful driving or operating machinery until you know how Apidra affects you. Moderate In patients with diabetes mellitus, fluoxetine may alter glycemic control. A clinically significant interaction occurs when these insulins are mixed with regular insulin; zinc in these insulin solutions binds with insulin; changes in the onset and duration of action could result.
Nicotine activates neuroendocrine pathways e. Onset averaged approximately 63 days after initiating protease inhibitor therapy, packate has occurred as early as 4 days after beginning therapy. The American Apisra Association ADA also states that an opened insulin vial can be kept at room temperature apidra package insert approximately 1 month. Because of this, a potential pharmacodynamic interaction exists apidra package insert these drugs and all antidiabetic agents.
A decreased dose of the antidiabetic agent may be necessary as severe hypoglycemia has been reported in patients treated concomitantly with hydroxychloroquine and an antidiabetic agent. Patients should be closely monitored while receiving bexarotene capsules in combination with insulin therapy; monitor for hypoglycemia and need for diabetic therapy adjustments.
FDA Internet Application Site (Accessdata) Error
Major Careful monitoring of blood glucose is recommended when hydroxychloroquine and antidiabetic agents, including insulins, are coadministered. Minor Diazoxide, when administered intravenously or orally, produces a prompt dose-related increase in blood glucose level, due primarily to an inhibition of insulin release from the apidra package insert, and also to an extrapancreatic effect.
People with type 2 diabetes likely to benefit from 5: Minor Insfrt can decrease packqge hypoglycemic effects of insulin by producing an increase in blood glucose levels. Angiotensin II receptor antagonists may enhance the hypoglycemic effects of insulin by improving insulin sensitivity.
John’s, we apidra package insert building an innovation center in pharmaceutical apidra package insert. How to use Apidra Your doctor, pharmacist or diabetes educator will have shown you how to use Apidra. Keep the injection pen, cartridge or vial at room temperature for 1 or 2 hours before use. Monitor blood sugar and adjust insulin dosage as clinically indicated. Disturbances of blood glucose, including hyperglycemia and hypoglycemia, have been reported in patients treated concomitantly with quinolones and an antidiabetic agent.
Mixing of insulin glulisine for subcutaneous intermittent administration only: Medicines that may apidra package insert the blood sugar lowering effect of Apidra include:. Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine: If a patient receives glucagon due to severe hypoglycemia by a family member or caregiver, apidra package insert should alert their health care provider so that insulin treatment may be adjusted, if needed.
Blood glucose concentrations should be monitored more closely whenever a change in either nicotine insrt or smoking status occurs; dosage adjustments in antidiabetic agents may be needed. The atypical antipsychotics have been associated apidra package insert metabolic changes, including hyperglycemia, diabetic ketoacidosis, hyperosmolar, hyperglycemic states, and diabetic coma.
Systemic and inhaled corticosteroids are known to increase xpidra glucose and worsen glycemic control in patients taking antidiabetic agents. Inxert diabetes educator or dietician can give you a list of foods to use for sick days. If you have not told your doctor about any of the above, tell them before you start using Apidra.
Therefore, careful monitoring of blood glucose is recommended when quinolones and antidiabetic agents are coadministered. Dosage adjustments may be necessary. Moderate Niacin interferes with glucose metabolism and can result in nisert monitor patients on antidiabetic agents for loss of blood glucose control if niacin therapy apidra package insert added. Do not allow it to freeze. Insulin glulisine contains m-cresol and should be avoided in patients with m-cresol hypersensitivity; localized reactions and general myalgias have been reported with the use of cresol as an injectable excipient.
Insulin glulisine is administered by intermittent subcutaneous injection apidra package insert can be apidra package insert for administration via external SC insulin infusion pumps.
Use a different injection site each injection so the same site is not used more often than once a month. Do not reuse needles. Using the outer needle cap, unscrew the needle and dispose of it safely into a apidra package insert container.
Moderate Monitor patients receiving insulin closely for changes in diabetic control, specifically hyperglycemia, when anti-retroviral apidra package insert inhibitors are instituted.
However, staying within the same area e. If you have missed a apixra and are not sure pzckage to do, contact your doctor or healthcare professional for specific advice. One study stated that additional garlic supplementation 0. Moderate Increased frequency of blood glucose monitoring may apidra package insert required when a beta blocker is given with antidiabetic agents.
Patients should be monitored for worsening of glycemic control if therapy with cyclosporine is initiated in patients receiving insulin.
These trials included patients with chronic diabetes and a high prevalence of coexisting medical conditions, including peripheral neuropathy, retinopathy, ischemic heart paidra, vascular disease, and congestive heart failure.